Mekinist: Precautions and Warnings

Mekinist tablets mainly contain trametinib as an active ingredient. This medication is a MEK inhibitor, which is a sort of targeted therapy called signal transduction inhibitor. It helps resist or block the growth and spread of melanoma cells. 

This medicine is supplied as a form of tablet for oral administration. The recommended daily dose is trametinib 2 mg, should be consumed orally once a day until the disease progression. Consume at least 1 hour prior to or 2 hours following a meal. Do not consume a missed or forgotten dose within 12 hours of the upcoming dose. 

Precautions:

  • Take prescription by a healthcare practitioner before buying trametinib. 
  • You should check that the pharmacy/wholesaler from which you are ordering trametinib is licensed. 
  • Never order trametinib from a wholesaler/pharmacy that does not ask for a prescription letter for making a purchase.
  • In case any discrepancy in the description, never rely on the online wholesaler/pharmacy. 
  • You must check the pharmacy/wholesaler accreditation and reliability. 
  • Do not share trametinib prescription medication with anyone even having the similar problems.
  • Avoid falling for fat discounts, decreased mekinist cost may be given to hook customers. 
  • Never accept trametinib if the packaging is damaged/puffed up.
  • Never accept trametinib if it doesn't look authentic or look tampered with.

Warnings:

  • Retinal pigment epithelial detachments (RPED) may occur while on treatment with trametinib. 
  • Based on its mechanism of action, this medicine can be responsible for causing fetal harm when administered to a pregnant woman. 
  • Hemorrhages may occur when this medicine is used together with the dabrafenib.
  • Venous thromboembolism may occur when this drug is used together with dabrafenib.
  • Hyperglycemia may occur if mekinist is used together with dabrafenib and with dabrafenib as a single agent.
  • Serious skin toxicity may occur when this medicine is given as a single agent or when used together with dabrafenib.
  • Uveitis and iritis may occur when this drug is used together with dabrafenib and with dabrafenib as a single agent. 


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